Levann "jA" Sugar Balance, 30 sachets + 60 capsules

Dissolve 1 sachet of the product in 150 ml of lukewarm water, stirring vigorously for about a minute, sip 2 capsules with the prepared solution from the sachet. Consume immediately after preparation, preferably after a meal. The recommended daily dose is 1 sachet and 2 capsules. 1 serving of the product provides 2 kcal.

Store the product in a closed container, in a dry place, at room temperature, away from direct sunlight, out of the reach of children.

The product is intended for adults. Do not exceed the recommended portion to be taken per day. Pregnant and breastfeeding women should consult a doctor before use. Do not use the product in case of hypersensitivity to any of its components. Do not use the supplement after the minimum shelf life date. The dietary supplement should not be used as a substitute for a varied diet.

One package of Levann “jA” Sugar Balance contains 30 sachets and 60 capsules. The package is sufficient for 1 month of supplementation.

At the center of Levann “jA” Sugar Balance is SelectSIEVE® Apple - a unique, natural ingredient developed based on the latest scientific advances. Its efficacy and safety have been confirmed in clinical studies [1,2,3,4].

Efficacy in short-term glucose regulation

The short-term study involved 20 subjects aged 18-70 with elevated fasting glucose levels (100-125 mg/dL). Participants took 300 mg of SelectSIEVE® Apple daily for 14 days, with the following results:

• Reduced glucose absorption by 39.2%, reducing blood sugar spikes.
• Reduction in peak glucose levels by 14%, confirming effectiveness in stabilizing glycemia.
• Slowing the release of glucose into the blood by 27%, ensuring an even supply of energy over a longer period of time.

Long-term effects on metabolic health

Further research focused on the long-term effects of SelectSIEVE® Apple. Participants took the supplement for 8 weeks, which resulted in even more comprehensive results:

• A 15.1% decrease in fasting glucose levels, confirming its ability to provide long-term support for glycemic balance.
• Improved cardiometabolic health: a 6.6% increase in heart rate capacity and an 11.2% decrease in the leptin/adiponectin ratio, attest to improved cardiovascular function and fat metabolism.
• Liver support: a decrease in AST enzyme levels by 6.6% and Gamma-GT by 12.7%, indicating improved detoxification functions of the body.
• Uric acid regulation: decrease in uric acid levels by 10.5%, supporting joint health and kidney function.

Chromium* is an essential micronutrient that supports proper macronutrient metabolism, providing the body with energy for the day. Its role is crucial in maintaining stable blood glucose levels, which helps avoid sudden drops in strength and uncontrolled appetite. In addition, chromium is an important component of the glucose tolerance factor, which aids in the transport of sugar into cells, thus supporting metabolic balance and optimal functioning of the body.

*Chromium contributes to maintaining normal macronutrient metabolism and helps maintain normal blood glucose levels.

Berberine*, extracted from barberry root, is a true ally in maintaining normal blood sugar levels. It aids in the transport of glucose into cells, and at the same time can reduce excessive glucose production by the liver, thus supporting the stabilization of sugar metabolism. Additionally, berberine has a beneficial effect on fat metabolism, helping to maintain optimal blood triglyceride levels [12,13,14].

*Berberine extract helps improve blood glucose control and promotes control of plasma triglyceride levels.

White mulberry* contains a unique compound, deoxynojirimycin, which slows the breakdown of complex sugars into simple sugars. As a result, it may contribute to maintaining stable blood glucose levels, preventing rapid fluctuations and supporting steady energy levels. In addition, white mulberry improves the body's use of insulin, helping cells absorb glucose more efficiently [15,16].

*White mulberry extract helps control blood sugar levels.

Inositol is a silent but highly effective ally in maintaining stable blood glucose levels. Its key role is to support the production of insulin signal transmitters, which helps the body efficiently capture glucose and transport it to the muscles. As a result, it can contribute to lowering blood sugar levels and promoting normal carbohydrate metabolism [5,6].

Apple cider vinegar is not only a popular culinary ingredient, but also a valuable ally in maintaining stable blood sugar levels. Its action is to slow down gastric emptying, which prolongs the time for starch to be broken down into simple sugars. As a result, glucose is released gradually, preventing sudden spikes in blood glucose levels and promoting energy stability in the body [7,8].

Alpha-lipoic acid (ALA) is a comprehensive support for glycemic balance and proper metabolism. It participates in key metabolic processes, facilitating cells to efficiently use energy from food. As a powerful antioxidant, it helps reduce oxidative stress, neutralizing the damaging effects of free radicals and supporting whole body health [9,10,11].

1. Bortolotto V., Piangiolino C., Giardina S., «SelectSIEVE® Apple PCQ: A synergic complex to fight against menopause trouble» Nutracos March /April 2013
2. Bortolotto V., Piangiolino C., «Apple biophenols synergistic complex and its potential benefits for cardiovascular health» Nutrafood 2013
3. Puoci F., Nobile V., Zanzottera F., Piangiolino C., «Potential control in calories intake and prolonged satiety effect promoted by apple polyphenols» Agrofoods, November / December 2014
4. Cicero et al., «Effect of apple polyphenols on vascular oxidative stress and endothelium function: a translational study» Molecular Nutrition & Food Research · July 2017
5. Miñambres I, Cuixart G, Gonçalves A, Corcoy R. Effects of inositol on glucose homeostasis: Systematic review and meta-analysis of randomized controlled trials. Clin Nutr. 2019;38(3):1146-1152. doi:10.1016/j.clnu.2018.06.957
6. Wei J, Yan J, Yang H. Inositol Nutritional Supplementation for the Prevention of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Nutrients. 2022;14(14):2831. Published 2022 Jul 9. doi:10.3390/nu14142831
7. Jafarirad S, Elahi MR, Mansoori A, Khanzadeh A, Haghighizadeh MH. The improvement effect of apple cider vinegar as a functional food on anthropometric indices, blood glucose and lipid profile in diabetic patients: a randomized controlled clinical trial. Front Clin Diabetes Healthc. 2023;4:1288786. Published 2023 Nov 13. doi:10.3389/fcdhc.2023.1288786
8. Gheflati A, Bashiri R, Ghadiri-Anari A, Reza JZ, Kord MT, Nadjarzadeh A. The effect of apple vinegar consumption on glycemic indices, blood pressure, oxidative stress, and homocysteine in patients with type 2 diabetes and dyslipidemia: A randomized controlled clinical trial. Clin Nutr ESPEN. 2019;33:132-138. doi:10.1016/j.clnesp.2019.06.006
9. Capece U, Moffa S, Improta I, et al. Alpha-Lipoic Acid and Glucose Metabolism: A Comprehensive Update on Biochemical and Therapeutic Features. Nutrients. 2022;15(1):18. Published 2022 Dec 21. doi:10.3390/nu15010018
10. Capece U, Moffa S, Improta I, Di Giuseppe G, Nista EC, Cefalo CMA, Cinti F, Pontecorvi A, Gasbarrini A, Giaccari A, Mezza T. Alpha-Lipoic Acid and Glucose Metabolism: A Comprehensive Update on Biochemical and Therapeutic Features. Nutrients. 2022 Dec 21;15(1):18. doi: 10.3390/nu15010018. PMID: 36615676; PMCID: PMC9824456.
11. Nguyen H, Pellegrini MV, Gupta V. Alpha-Lipoic Acid. In: StatPearls. Treasure Island (FL): StatPearls Publishing; January 26, 2024.
12. Safari Z, Farrokhzad A, Ghavami A, et al. The effect of barberry (Berberis vulgaris L.) on glycemic indices: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Med. 2020;51:102414. doi:10.1016/j.ctim.2020.102414
13. Moazezi Z, Qujeq D. Berberis Fruit Extract and Biochemical Parameters in Patients With Type II Diabetes. Jundishapur J Nat Pharm Prod. 2014;9(2):e13490. Published 2014 Apr 7. doi:10.17795/jjnpp-13490
14. Singh J, Kakkar P. Antihyperglycemic and antioxidant effect of Berberis aristata root extract and its role in regulating carbohydrate metabolism in diabetic rats. J Ethnopharmacol. 2009;123(1):22-26. doi:10.1016/j.jep.2009.02.038
15. Asai A, Nakagawa K, Higuchi O, et al. Effect of mulberry leaf extract with enriched 1-deoxynojirimycin content on postprandial glycemic control in subjects with impaired glucose metabolism. J Diabetes Investig. 2011;2(4):318-323. doi:10.1111/j.2040-1124.2011.00101.x
16. Cui W, Luo K, Xiao Q, et al. Effect of mulberry leaf or mulberry leaf extract on glycemic traits: a systematic review and meta-analysis. Food Funct. 2023;14(3):1277-1289. Published 2023 Feb 6. doi:10.1039/d2fo02645g